Nissan Reshi Mushroom or Lucid Ganoderma Tea is a combination of high-grade Lucid Ganoderma wall-broken powder with high quality flowers like Chrysanthemum, Rose and Osmanthus flowers to provide many health benefits such as strengthening body resistance, invigorating the spleen and replenishing Qi. It has several proven health advantages and should be consumed on a regular basis for maximum effect.

GLC extract effectively reduced the invasiveness of MDA-MB-231 breast cancer cells by inhibiting their expression of Urokinase Plasminogen Activator (uPA). Furthermore, it significantly mitigated any damage done to liver tissue caused by Tertbutyl Hydroperoxide peroxide exposure in mice.

Anti-cancer

Ganoderma lucidum, commonly referred to as “Gano,” is an edible mushroom known for its health benefits and longevity properties. This mushroom contains polysaccharides and triterpenoids with anti-tumor, immunostimulatory, and antioxidant properties; such compounds have the power to reduce DNA damage caused by free radicals as well as block tumor cells from growing further.

Ganoderma extracts also possess significant DPPH radical scavenging and chelating activities, and have the ability to inhibit apoptosis while increasing glutathione and superoxide dismutase production in cancer cells. They also show anti-inflammatory and hypoglycemic effects.

G. lucidum extracts were shown to significantly decrease neointimal thickening and prevent the development of apoptosis when tested in a carotid-artery ligation model in mice (Fatmawati et al. 2009), with its methanol fruit body extract demonstrating strong aldose reductase inhibitive activity via its lanostane-type triterpenoid Ganoderic Acid Df showing stronger inhibition than FDA approved T2DM medications as well as inhibited a-glucosidase activity as well.

Anti-aging

Ganoderma lucidum, also known as Lucid Ganoderma Tea, is an antioxidant-rich medicinal mushroom with anti-aging benefits. Used in traditional Chinese medicine to strengthen body resistance and invigorate spleen function while replenishing Qi, as well as strengthening immunity against cancer and protecting against it, its anti-ageing benefits can be attributed to antioxidant properties of this tea.

GLPs can inhibit UVB-induced MMP-1 expression and increase procollagen protein expression in fibroblasts. They also scavenge free radicals and reactive oxygen species to delay the aging process (Lee et al., 2018).

Lucid Ganoderma not only boasts anti-aging benefits, but it is also cardioprotective. When applied to an ischaemia and reperfusion isolated perfused rat heart model, lucid Ganoderma extract increased activity of antioxidant enzymes SOD and CAT which protect against oxidative damage to protect the heart from further oxidation damage. Thus making it a promising candidate for treating cardiovascular diseases; further clinical studies must be conducted with large controlled trials to test its efficacy.

Anti-diabetes

Ganoderma lucidum extract is known to possess anti-diabetes and anti-hyperlipidemic effects, as well as possessing anti-inflammatory and immunostimulatory benefits. Furthermore, it inhibits reactive oxygen species production while decreasing oxidative DNA damage.

G. lucidum contains polysaccharides that can boost insulin secretion, decrease hepatic glucose output, and enhance adipose and skeletal muscle glucose disposal (Hikino et al. 1985). Furthermore, water extraction of its fruit body showed antihyperglycaemic activity both in normal rats and those treated with alloxan (a medication to induce hyperglycaemic states).

Studies conducted on mice (Berger et al., 2004) have demonstrated that extracts of G. lucidum from both hexane and acetone solvents can effectively lower cholesterol (Berger et al.). Hamsters and minipigs fed 2.5 and 5% dried G. lucidum reduced total and LDL-C cholesterol while its organic fractions suppressed HMG-CoA reductase activity ex vivo assays; suggesting it might serve as an effective therapy against cardiovascular diseases.

Anti-hypertension

Ganoderma lucidum, commonly referred to in China and Japan as Lingzhi or Reishi respectively, is an edible mushroom with numerous health advantages. Packed full of polysaccharides, triterpenoids and nucleosides with antioxidant and anti-inflammatory effects – Lingzhi/Reishi can improve sleep quality, immune system performance as well as lower cholesterol and triglyceride levels while protecting livers and kidneys from harm.

Ganoderma spore oil has been demonstrated to possess cardioprotective effects in animal models. One such study involved administering it to rats with chronic transverse aortic constriction (TAC), wherein this treatment improved ejection fraction and corrected left ventricular hypertrophy.

The invention involves the preparation of a health product summer drink angle’s tea made by mixing lucid ganoderma fruiting bodies with other raw materials such as licorice, chrysanthemum petals, sophora flower bud pieces, jujube beans and Biluochun tea in certain ratios in order to maximize synergistic effects between each ingredient.

Anti-asthma

This invention describes a summer ginseng lucid ganoderma tea with cordyceps (1-99% by weight), lucid ganoderma (2-25 weight%), Radix Ginseng (0-10 weight%), Fructus Lycii (0-25 weight%) and green tea (0-60 weight%) as active ingredients, providing health-care functions including improving immunity, delaying senility, nourishing yin and tonifying qi as well as relieving summer heat relief, reducing blood fat content as well as consolidating benefit essence etc. Furthermore it offers the advantages of being easy and highly effective!

Ganoderma belongs to the Polyporales order and is one of the most widespread wood-decaying basidiomycete fungi globally (Fig 2). It has antitumor, antifibrosis and other medicinal uses (Jin et al. 2016), and can be divided into sections such as Ganoderma, Amauroderma or Trachyderma depending on whether its spore wall contains evident spines (see Fig 2).

Anti-inflammation

G. lucidum contains polysaccharides and triterpenes with anti-inflammatory, antihypertensive, and hypoglycaemic properties; however, large-scale clinical trials have failed to support these claims. Therefore, further research needs to be conducted in order to standardise Lingzhi preparations as well as assess their effects in various populations.

GLPs can reduce MMP-1 expression, increase procollagen expression, scavenge free radicals produced during UVB radiation exposure to fibroblasts and inhibit both phosphorylation of ERK as well as secretion of proinflammatory cytokines (Lee et al. 2018).

Polysaccharides and triterpenes from G. lucidum have been shown to protect against neurodegenerative diseases such as Alzheimer’s, Parkinson’s disease, cardiovascular disorders and neural repair disorders such as Multiple Sclerosis. Furthermore, they promote neural repair in damaged cells due to reducing inflammation, oxidative stress and inhibiting cell death – benefits which may also extend into cardiovascular disorders and cancer prevention.

Anti-tumor

Ganoderma lucidum, commonly referred to in China and Japan as Lingzhi or Reishi respectively, is an edible mushroom used for treating various illnesses. Its polysaccharides, triterpenes, sterols and phenolic compounds have been proven to prevent or delay cancerous tumor development through cell cycle inhibition, suppression of tumor growth suppression and induction of apoptosis.

Studies conducted on animals have revealed the antioxidant, hypoglycaemic, and lipid-reducing properties of G. lucidum extracts as well as its water-soluble polysaccharide fraction FYGL as possessing antitumor effects both in vivo and in vitro.

G. lucidum contains water-soluble peptidoglycans such as Ganoderan B and C that exhibit hypoglycaemic activity in normal and diabetic mice, providing hypoglycaemic benefits through enhanced insulin secretion, decreased hepatic glucose output, as well as increasing adipose and skeletal muscle glucose disposal rates and improving blood hematology and lipid profiles.

Anti-oxidant

Ganoderma lucidum polysaccharides (GLPs) exhibit powerful antioxidant effects and are proven to inhibit MMP-1 production, increase procollagen expression and neutralise free radicals while providing skin whitening and antiageing properties. GLPs contain Ganoderan which is an b(1,3) bioactive glucan with branched structures and high molecular weight – making these GLPs great additions for the treatment of wrinkles!

GLPs’ reducing activity correlates with their ability to convert Fe3+ to Fe2+, suggesting they act as electron donors and can prevent damage due to oxidative stress.

G. lucidum spore extract reduced hepatotoxicity caused by tertbutyl hydrogen peroxide exposure in rat liver cells and increased glutathione and superoxide dismutase levels, while also inhibiting lipid peroxidation and suppressing apoptosis. Lucidinic acid and lupinoic acid inhibit HMG-CoA reductase, the target enzyme for cholesterol-reducing statin drugs; oral G. lucidum extracts prevented neointimal thickening through carotid artery-ligament mouse model research.

Anti-stress

Ganoderma lucidum is an important medicinal mushroom in traditional Chinese medicine, offering numerous health benefits such as strengthening body resistance, stimulating the spleen and replenishing Qi. Furthermore, Ganoderma contains numerous active compounds including polysaccharides, triterpenoids and antioxidant peptides – these have all been demonstrated to possess anti-stress, antioxidant and immune-regulatory properties.

Reishi has long been used as a natural way of relieving stress-related conditions such as coronary artery disease. Reishi may strengthen the heart, lower cholesterol, and inhibit platelet aggregation; its constituent ganoderic acids have also been proven to lower risk factors associated with cardiovascular disease; its tetracyclic constituents come from fruiting bodies and spores of the fungus and have anti-stress, antioxidant, and antitumor properties attributed to its therapeutic effects on AD.

Anti-spasmodic

Ganoderma lucidum, more commonly known by its Chinese names Lingzhi or Reishi, is a woody mushroom used widely in Traditional Chinese Medicine due to its wide array of benefits. Studies have revealed it to possess antispasmodic properties which may benefit those suffering from stomach and intestinal conditions, polysaccharides and oxygenated triterpenoids found in G. lucidum as the primary therapeutic agents; polysaccharides and oxygenated triterpenoids found within it may reduce cholesterol by inhibiting HMG-CoA reductase like statin drugs do;

Ganoderma spore oil not only has antispasmodic effects, but it is also shown to provide cardioprotection benefits. It slows down pressure overload-induced cardiomyopathy by normalising ejection fraction and correcting left ventricular hypertrophy in mouse models, while increasing expression of a circular RNA molecule which regulates autophagy via inhibition of p38 MAPK activity.